(19)
(11) EP 0 817 630 A1

(12)

(43) Date of publication:
14.01.1998 Bulletin 1998/03

(21) Application number: 96910528.0

(22) Date of filing: 25.03.1996
(51) International Patent Classification (IPC): 
C07D 233/ 64( . )
A61K 31/ 215( . )
A61P 35/ 00( . )
C07C 323/ 59( . )
C07D 233/ 56( . )
A61K 31/ 195( . )
A61K 31/ 415( . )
A61P 43/ 00( . )
C07D 233/ 54( . )
C07D 521/ 00( . )
(86) International application number:
PCT/US1996/003980
(87) International publication number:
WO 1996/030015 (03.10.1996 Gazette 1996/44)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 29.03.1995 US 19950413137
29.03.1995 US 19950412830

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • CICCARONE, Terrence, M.
    Rahway, NJ 07065 (US)
  • WILLIAMS, Theresa, M.
    Rahway, NJ 07065 (US)
  • MacTOUGH, Suzanne, C.
    Rahway, NJ 07065 (US)

(74) Representative: Thompson, John Dr., et al 
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE