INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - Patent 0820445

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(11)

EP 0 820 445 A1

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(43)	Date of publication:
	28.01.1998 Bulletin 1998/05

(21)	Application number: 96909851.0

(22)	Date of filing: 25.03.1996

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International Patent Classification (IPC):

C07D 233/ 64^{( . )}
A61K 31/ 496^{( . )}
A61P 3/ 08^{( . )}
A61P 15/ 00^{( . )}
A61P 31/ 12^{( . )}
A61P 43/ 00^{( . )}
C07D 241/ 04^{( . )}
C07D 295/ 192^{( . )}
C07D 401/ 14^{( . )}
C07D 403/ 12^{( . )}

A61K 31/ 495^{( . )}
A61P 1/ 16^{( . )}
A61P 13/ 02^{( . )}
A61P 27/ 02^{( . )}
A61P 35/ 00^{( . )}
C07D 233/ 54^{( . )}
C07D 241/ 08^{( . )}
C07D 401/ 06^{( . )}
C07D 403/ 06^{( . )}

(86)	International application number:
	PCT/US1996/004019

(87)	International publication number:
	WO 1996/030343 (03.10.1996 Gazette 1996/44)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
	Designated Extension States:
	LT LV SI

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Priority:

29.03.1995 US 19950412829
06.06.1995 US 19950470690
01.03.1996 US 19960600728

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	ANTHONY, Neville, J. Rahway, NJ 07065 (US) CICCARONE, Terrence, M. Rahway, NJ 07065 (US) GOMEZ, Robert, P. Rahway, NJ 07065 (US) HUTCHINSON, John, H. Rahway, NJ 07065 (US) WILLIAMS, Theresa, M. Rahway, NJ 07065 (US) DINSMORE, Christopher, J. Rahway, NJ 07065 (US) STOKKER, Gerald, E. Rahway, NJ 07065 (US) HARTMAN, George, D. Rahway, NJ 07065 (US)

(74)	Representative: Thompson, John Dr., et al
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE