(19)

(11)

EP 0 822 992 A1

(12)

(43) Date of publication: 11.02.1998 Bulletin 1998/07 (21) Application number: 96911209.0 (22) Date of filing: 27.02.1996

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C12N 15/ 113( . ) G01N 33/ 58( . ) C12N 9/ 00( . ) C12Q 1/ 68( . ) (86) International application number: PCT/US1996/002380 (87) International publication number: WO 1996/027026 (06.09.1996 Gazette 1996/40)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV SI (30) Priority: 27.02.1995 IL 19950112799 26.10.1995 IL 19950115722 (71) Applicant: Intelligene Ltd. Jerusalem 91071 (IL)	(72) Inventors: ASHER, Nathan 99900 Bet-Shemesh (IL) TIKOCHINSKI, Yaron 92107 Jerusalem (IL) KRUPP, Guido D-24118 Kiel (DE) GRINBERG, Jacob 62664 Tel-Aviv (IL) FRIEDMANN, Adam 47208 Ramat Hasharon (IL) (74) Representative: Dzieglewska, Hanna Eva, et al  Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)