AZOCOMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION - Patent 0823894

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EP 0 823 894 A1

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(43)	Date of publication:
	18.02.1998 Bulletin 1998/08

(21)	Application number: 96913856.0

(22)	Date of filing: 01.05.1996

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International Patent Classification (IPC):

G01N 33/ 68^{( . )}
C07C 59/ 64^{( . )}
C07C 245/ 08^{( . )}
C07C 309/ 46^{( . )}
C07D 209/ 48^{( . )}
C07D 213/ 80^{( . )}
C07D 221/ 14^{( . )}
C07D 237/ 32^{( . )}
C07D 261/ 20^{( . )}
C07D 265/ 26^{( . )}
C07D 295/ 22^{( . )}
C07D 413/ 06^{( . )}
C09B 35/ 14^{( . )}

A61K 49/ 00^{( . )}
C07C 63/ 66^{( . )}
C07C 245/ 10^{( . )}
C07C 309/ 47^{( . )}
C07D 213/ 02^{( . )}
C07D 217/ 24^{( . )}
C07D 237/ 28^{( . )}
C07D 257/ 04^{( . )}
C07D 265/ 02^{( . )}
C07D 271/ 10^{( . )}
C07D 403/ 06^{( . )}
C07F 7/ 22^{( . )}

(86)	International application number:
	PCT/US1996/005918

(87)	International publication number:
	WO 1996/034853 (07.11.1996 Gazette 1996/49)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

01.05.1995 US 19950432019

(60)	Divisional application:
	01103705.8 / 1110945

(71)	Applicant: UNIVERSITY OF PITTSBURGH
	Pittsburgh, Pennsylvania 15260 (US)

(72)	Inventors:
	KLUNK, William, E. Pittsburgh, PA 15218 (US) PETTEGREW, Jay, W. Pittsburgh, PA 15208 (US) MATHIS, Chester, A., Jr. Pittsburgh, PA 15238 (US)

(74)	Representative: Sheard, Andrew Gregory
	Kilburn & Strode 30, John Street London WC1N 2DD London WC1N 2DD (GB)

(54)	AZOCOMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION