(19)
(11) EP 0 824 360 A1

(12)

(43) Date of publication:
25.02.1998 Bulletin 1998/09

(21) Application number: 96911776.0

(22) Date of filing: 16.04.1996
(51) International Patent Classification (IPC): 
A61K 39/ 385( . )
A61P 37/ 00( . )
 A61K 39/ 39( . )
C07K 14/ 285( . )
(86) International application number:
PCT/US1996/005226
(87) International publication number:
WO 1996/032963 (24.10.1996 Gazette 1996/47)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 17.04.1995 US 19950422830
07.06.1995 US 19950472640
06.12.1995 US 19950568342

(71) Applicants:
  • HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE
    Rockville, MD 20852 (US)
  • SMITHKLINE BEECHAM BIOLOGICALS S.A.
    1330 Rixensart (BE)

(72) Inventors:
  • SNAPPER, Clifford M.
    Potomac, MD 20854 (US)
  • MOND, James J.
    Potomac, MD 20854 (US)
  • CAPIAU, Carine
    7050 Erbisocul Mons (BE)
  • HAUSER, Pierre
    1325 Chaumont Gistoux (BE)
  • PRIEELS, Jean-Paul
    1200 Brussels (BE)

(74) Representative: Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät 
Maximilianstrasse 58
80538 München
80538 München (DE)

   


(54) INDUCTION AND ENHANCEMENT OF THE IMMUNE RESPONSE TO POLYSACCHARIDES WITH BACTERIAL LIPOPROTEINS