(19)
(11) EP 0 824 583 A1

(12)

(43) Date of publication:
25.02.1998 Bulletin 1998/09

(21) Application number: 96913354.0

(22) Date of filing: 03.05.1996
(51) International Patent Classification (IPC): 
G01N 33/ 573( . )
A61K 31/ 045( . )
A61K 31/ 155( . )
A61K 31/ 20( . )
A61K 31/ 202( . )
A61K 31/ 352( . )
A61K 31/ 4439( . )
A61K 33/ 06( . )
A61K 38/ 08( . )
A61K 38/ 20( . )
A61K 45/ 00( . )
A61P 3/ 00( . )
A61P 9/ 00( . )
A61P 29/ 00( . )
A61P 35/ 04( . )
C12N 9/ 02( . )
C12Q 1/ 26( . )
A61K 31/ 00( . )
A61K 31/ 05( . )
A61K 31/ 195( . )
A61K 31/ 201( . )
A61K 31/ 35( . )
A61K 31/ 44( . )
A61K 31/ 575( . )
A61K 38/ 00( . )
A61K 38/ 18( . )
A61K 38/ 46( . )
A61K 48/ 00( . )
A61P 3/ 10( . )
A61P 9/ 10( . )
A61P 35/ 00( . )
A61P 37/ 00( . )
C12N 9/ 99( . )
G01N 33/ 68( . )
(86) International application number:
PCT/US1996/006328
(87) International publication number:
WO 1996/034943 (07.11.1996 Gazette 1996/49)
(84) Designated Contracting States:
DE FR GB

(30) Priority: 04.05.1995 US 19950434681

(71) Applicant: CITY OF HOPE
Duarte California 91010-0269 (US)

(72) Inventors:
  • NADLER, Jerry, L.
    La Crescenta, CA 91214 (US)
  • NATARAJAN, Rama
    Hacienta Heights, CA 91745 (US)

(74) Representative: Dowden, Marina 
Elkington and Fife Prospect House, 8 Pembroke Road
Sevenoaks, Kent TN13 1XR
Sevenoaks, Kent TN13 1XR (GB)

   


(54) HUMAN LEUKOCYTE 12-LIPOXYGENASE AND ITS ROLE IN THE PATHOGENESIS OF DISEASE STATES