(19)

(11)

EP 0 825 995 A1

(12)

(43) Date of publication: 04.03.1998 Bulletin 1998/10 (21) Application number: 96915094.0 (22) Date of filing: 10.05.1996

(51) International Patent Classification (IPC):  A61K 31/ 70( . ) A61K 31/ 7048( . ) C07H 17/ 08( . ) A61K 31/ 7042( . ) A61P 31/ 04( . ) (86) International application number: PCT/GB1996/001144 (87) International publication number: WO 1996/035701 (14.11.1996 Gazette 1996/50)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 13.05.1995 PL 19950308583 (71) Applicant: BRITISH TECHNOLOGY GROUP LIMITED London SE1 6BU (GB)	(72) Inventors: BOROWSKI, Edward PL-80-278 Gdansk (PL) GRZYBOWSKA, Jolanta PL-80-269 Gdansk (PL) SOWINSKI, Pawel PL-81-862 Sopot (PL) GUMIENIAK, Jerzy Stafford, TX 77477 (US) CZERWINSKI, Andrzej Stafford, TX 77477 (US) (74) Representative: Dolan, Anthony Patrick  British Technology Group 101 Newington Causeway London SE1 6BU London SE1 6BU (GB)