(19)

(11)

EP 0 831 793 A1

(12)

(43) Date of publication: 01.04.1998 Bulletin 1998/14 (21) Application number: 96918313.0 (22) Date of filing: 04.06.1996

(51) International Patent Classification (IPC):  C07D 339/ 04( . ) A61K 9/ 16( . ) A61K 31/ 70( . ) A61K 38/ 00( . ) A61P 7/ 04( . ) A61K 9/ 107( . ) A61K 9/ 51( . ) A61K 35/ 16( . ) A61K 47/ 48( . ) B01J 13/ 00( . ) (86) International application number: PCT/US1996/009458 (87) International publication number: WO 1996/039128 (12.12.1996 Gazette 1997/02)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV SI (30) Priority: 06.06.1995 US 19950471650 09.11.1995 US 19950554919 (71) Applicant: HEMOSPHERE, INC. Irvine, CA 92718 (US)	(72) Inventor: YEN, Richard, C., K. Yorba Linda, CA 92687 (US) (74) Representative: Baillie, Iain Cameron  c/o Ladas & Parry 52-54 High Holborn London WC1V 6RR London WC1V 6RR (GB)