(19)

(11)

EP 0 831 805 A1

(12)

(43) Date of publication: 01.04.1998 Bulletin 1998/14 (21) Application number: 96921263.0 (22) Date of filing: 03.06.1996

(51) International Patent Classification (IPC):  A61K 31/ 20( . ) A61K 36/ 02( . ) C12P 7/ 64( . ) A61K 31/ 202( . ) A61K 36/ 06( . ) (86) International application number: PCT/US1996/008649 (87) International publication number: WO 1996/040106 (19.12.1996 Gazette 1997/03)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 07.06.1995 US 19950479809 (60) Divisional application: 07075522.8 / 1886679 (60) Divisional application: 10182717.8 /  (71) Applicant: MARTEK BIOSCIENCES CORPORATION Columbia, MD 21045 (US)	(72) Inventors: KYLE, David, J. Catonsville, MA 21228 (US) LINSERT, Henry, Jr. Alexandria, VA 22306 (US) (74) Representative: Hallybone, Huw George, et al  CARPMAELS AND RANSFORD 43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)