(19)
(11)
EP 0 831 806 A1
(12)
(43)
Date of publication:
01.04.1998
Bulletin 1998/14
(21)
Application number:
96924270.0
(22)
Date of filing:
07.06.1996
(51)
International Patent Classification (IPC):
A61K
41/
00
( . )
A61K
31/
285
( . )
A61K
31/
70
( . )
A61K
45/
00
( . )
A61P
35/
00
( . )
C07D
273/
00
( . )
C07F
5/
06
( . )
A61K
31/
28
( . )
A61K
31/
555
( . )
A61K
38/
00
( . )
A61P
33/
02
( . )
A61P
43/
00
( . )
C07F
5/
00
( . )
C07F
15/
02
( . )
(86)
International application number:
PCT/US1996/010079
(87)
International publication number:
WO 1996/040108
(
19.12.1996
Gazette 1997/03)
(84)
Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
07.06.1995
US 19950487991
(71)
Applicant:
WASHINGTON UNIVERSITY
St. Louis, MO 63130 (US)
(72)
Inventors:
PIWNICA-WORMS, David, R.
St. Louis, MO 63124 (US)
SHARMA, Vijay
St. Louis, MO 63132 (US)
(74)
Representative:
Schlich, George William, et al
Mathys & Squire 100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)
(54)
MULTIDENTATE METAL COMPLEXES AND METHODS OF MAKING AND USING THEREOF