(19)
(11) EP 0 831 806 A1

(12)

(43) Date of publication:
01.04.1998 Bulletin 1998/14

(21) Application number: 96924270.0

(22) Date of filing: 07.06.1996
(51) International Patent Classification (IPC): 
A61K 41/ 00( . )
A61K 31/ 285( . )
A61K 31/ 70( . )
A61K 45/ 00( . )
A61P 35/ 00( . )
C07D 273/ 00( . )
C07F 5/ 06( . )
A61K 31/ 28( . )
A61K 31/ 555( . )
A61K 38/ 00( . )
A61P 33/ 02( . )
A61P 43/ 00( . )
C07F 5/ 00( . )
C07F 15/ 02( . )
(86) International application number:
PCT/US1996/010079
(87) International publication number:
WO 1996/040108 (19.12.1996 Gazette 1997/03)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 07.06.1995 US 19950487991

(71) Applicant: WASHINGTON UNIVERSITY
St. Louis, MO 63130 (US)

(72) Inventors:
  • PIWNICA-WORMS, David, R.
    St. Louis, MO 63124 (US)
  • SHARMA, Vijay
    St. Louis, MO 63132 (US)

(74) Representative: Schlich, George William, et al 
Mathys & Squire 100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) MULTIDENTATE METAL COMPLEXES AND METHODS OF MAKING AND USING THEREOF