(19)
(11) EP 0 831 920 A1

(12)

(43) Date of publication:
01.04.1998 Bulletin 1998/14

(21) Application number: 96913917.0

(22) Date of filing: 26.04.1996
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 31/ 27( . )
A61K 31/ 404( . )
A61K 31/ 47( . )
A61K 38/ 00( . )
C07D 209/ 20( . )
C07K 5/ 06( . )
C07K 5/ 072( . )
C12Q 1/ 68( . )
 A61K 31/ 165( . )
A61K 31/ 403( . )
A61K 31/ 405( . )
A61K 31/ 472( . )
A61P 25/ 28( . )
C07D 217/ 06( . )
C07K 5/ 065( . )
C12N 9/ 64( . )
(86) International application number:
PCT/US1996/006211
(87) International publication number:
WO 1996/039194 (12.12.1996 Gazette 1997/02)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 06.06.1995 US 19950467607
06.06.1995 US 19950469362

(71) Applicant: Athena Neurosciences, Inc.
South San Francisco, CA 94080 (US)

(72) Inventors:
  • TUNG, Jay, S.
    Belmont, CA 94002 (US)
  • SINHA, Sukanto
    San Francisco, CA 94127 (US)
  • MCCONLOGUE, Lisa
    San Francisco, CA 94127 (US)
  • TATSUNO, Gwen
    Oakland, CA 94611 (US)
  • ANDERSON, John
    San Francisco, CA 94132 (US)
  • SEMKO, Christopher, M., F.
    Fremont, CA 94539 (US)
  • CHRYSLER, Susanna
    Brisbane, CA 94132 (US)

(74) Representative: Dubois-Chabert, Guy, et al 
Société de Protection des Inventions 25, rue de Ponthieu
75008 Paris
75008 Paris (FR)

   


(54) NOVEL CATHEPSIN AND METHODS AND COMPOSITIONS FOR INHIBITION THEREOF