(19)

(11)

EP 0 832 205 A1

(12)

(43) Date of publication: 01.04.1998 Bulletin 1998/14 (21) Application number: 96921420.0 (22) Date of filing: 07.06.1996

(51) International Patent Classification (IPC):  A01K 67/ 027( . ) A61P 25/ 28( . ) C12N 15/ 09( . ) C12Q 1/ 02( . ) A61K 45/ 00( . ) C07K 14/ 47( . ) C12N 15/ 85( . ) (86) International application number: PCT/US1996/009679 (87) International publication number: WO 1996/040895 (19.12.1996 Gazette 1997/03)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 07.06.1995 US 19950486018 07.06.1995 US 19950486538 (71) Applicant: Athena Neurosciences, Inc. South San Francisco, CA 94080 (US)	(72) Inventors: MCCONLOGUE, Lisa, Claire San Francisco, CA 94127 (US) SEUBERT, Peter, A. South San Francisco, CA 94080 (US) (74) Representative: Bassett, Richard, et al  ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate Nottingham NG1 1LE Nottingham NG1 1LE (GB)