(19)
(11) EP 0 832 219 A2

(12)

(43) Date of publication:
01.04.1998 Bulletin 1998/14

(21) Application number: 96917584.0

(22) Date of filing: 11.06.1996
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61P 3/ 04( . )
C07K 14/ 575( . )
C07K 19/ 00( . )
C12N 1/ 19( . )
C12N 5/ 10( . )
C12P 21/ 02( . )
A61K 38/ 00( . )
C07K 14/ 47( . )
C07K 16/ 00( . )
C12N 1/ 15( . )
C12N 1/ 21( . )
C12N 15/ 12( . )
(86) International application number:
PCT/GB1996/001388
(87) International publication number:
WO 1997/000319 (03.01.1997 Gazette 1997/02)
(84) Designated Contracting States:
BE CH DE DK ES FR GB IT LI NL

(30) Priority: 13.06.1995 GB 19950011935

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford, Middlesex TW8 9EP (GB)

(72) Inventors:
  • BROWNE, Michael Joseph, SmithKline Beecham Pharm.
    Harlow, Essex CM19 5AD (GB)
  • CHAPMAN, Conrad Gerald, SmithKline Beecham Pharm.
    Harlow, Essex CM19 5AD (GB)
  • CLINKENBEARD, Helen Elizabeth, SmithKline Beecham
    Harlow, Essex CM19 5AD (GB)
  • ROBINSON, Jeffrey Hugh, SmithKline Beecham Pharm.
    Harlow, Essex CM19 5AD (GB)

(74) Representative: Rutter, Keith, Dr., et al 
SmithKline Beecham plc Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) CHIMERIC LEPTIN FUSED TO IMMUNOGLOBULIN DOMAIN AND USE