ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI......................................*JDIM350 (Ver 2.1 Jan 2001) 2999001/00832271CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120050302W173DEBibliographieENBibliographyFRBibliographieEP96922432.8199606061997120420000309enenen48428219950607US48545819950607US20050302200509199804011998142004122220045220040315200503022005097 7C 12N 15/87 A 7C 12N 15/88 B 7A 61K 48/00 B 7A 61K 9/127 BdeHERSTELLUNG VON LIPID-NUKLEINSÄURE PARTIKELN DUCH EIN HYDROPHOBISCHE LIPID-NUKLEINSÄUREE KOMPLEXE ZWISCHENPRODUKT UND ZUR VERWENDUNG IN DER GENTRANSFERenLIPID-NUCLEIC ACID PARTICLES PREPARED VIA A HYDROPHOBIC LIPID-NUCLEIC ACID COMPLEX INTERMEDIATE AND USE FOR GENE TRANSFERfrPARTICULES D'ACIDES NUCLEIQUES ET DE LIPIDES PREPAREES AU MOYEN D'UN INTERMEDIAIRE DE COMPLEXE HYDROPHOBE D'ACIDES NUCLEIQUES ET DE LIPIDES ET UTILISATION POUR TRANSFERER DES GENESWO-A-91/16024WO-A-93/12240WO-A-93/12756WO-A-93/24640WO-A-93/25673WO-A-95/02698WO-A-95/18863WO-A-95/35301WO-A-96/02655WO-A-96/10390WO-A-96/41873US-A- 5 208 036US-A- 5 279 833US-A- 5 283 185US-A- 5 578 475US-A- 5 641 662US-A- 5 656 743US-A- 5 703 055R. CORTESI ET AL.: "Effect of cationic liposome composition on in vitro cytotoxicity and protective effect on carried DNA." INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 139, no. 1,2, 9 August 1996 (1996-08-09), pages 69-78, XP000874084GAY-CAFFEY J K ET AL: "NOVEL POLYAMINOLIPIDS ENHANCE TH CELLULAR UPTAKE OF OLIGONUCLEOTIDES" JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 270, no. 52, 29 December 1995 (1995-12-29), pages 31391-31396, XP002017298 ISSN: 0021-9258WOUDE VAN DER I ET AL: "PARAMETERS INFLUENCING THE INTRODUCTION OF PLASMID DNA INTO CELLS BY THE USE OF SYNTHETIC AMPHIPHILES AS A CARRIER SYSTEM" BIOCHIMICA ET BIOPHYSICA ACTA. BIOMEMBRANES,NL,AMSTERDAM, vol. 1240, no. 1, 1 January 1995 (1995-01-01), pages 34-40, XP000600703 ISSN: 0005-2736DWARKI V J ET AL: "CATIONIC LIPOSOME-MEDIATED RNA TRANSFECTION" METHODS IN ENZYMOLOGY,US,ACADEMIC PRESS INC, SAN DIEGO, CA, vol. 217, 1 January 1993 (1993-01-01), pages 644-654, XP000600710 ISSN: 0076-6879FELGNER J ET AL: "CATIONIC LIPID-MEDIATED TRANSFECTION IN MAMMALIAN CELLS: LIPOFECTION" JOURNAL OF TISSUE CULTURE METHODS,NL,KLUWER ACADEMIC PUBLISHERS, AMSTERDAM, vol. 15, no. 2, 1 January 1993 (1993-01-01), pages 63-68, XP000600638 ISSN: 0271-8057FELGNER P L ET AL: "CATIONIC LIPOSOME MEDIATED TRANSFECTION" WESTERN PHARMACOLOGY SOCIETY. PROCEEDINGS,US,WESTERN PHARMACOLOGY SOCIETY, TUCSON, AZ, vol. 32, 1 January 1989 (1989-01-01), pages 115-121, XP000196640 ISSN: 0083-8969FELGNER J H ET AL: "ENHANCED GENE DELIVERY AND MECHANISM STUDIES WITH A NOVEL SERIES OF CATIONIC LIPID FORMULATIONS" JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 269, no. 4, 28 January 1994 (1994-01-28), pages 2550-2561, XP002010485 ISSN: 0021-925804022700.1148918420040923WHEELER, Jeffery, J.306 - 1340 W. 70th AvenueVancouver, British Columbia V6P 2Y8CABALLY, Marcel, B.SPC 11 Harding RoadBowen Island, British Columbia V0N 1G0CAZHANG, Yuan-PengSuite 105 40 East 11th AvenueVancouver, British Columbia V5T 2B8CAREIMER, Dorothy, L.Suite 202 55 East 12th AvenueVancouver, British Columbia V5T 4J4CAHOPE, Michael3550 West 11th AvenueVancouver, British Columbia V6R 2K2CACULLIS, Pieter, R.3732 West 1st AvenueVancouver, British Columbia V6R 1H4CASCHERRER, PeterApartment 301 2664 Birch StreetVancouver, British Columbia V6H 2T5CAINEX Pharmaceuticals Corp.01730523J 2429 - Mr/SvPharmaceuticals Corp., INEX1779 West 75th AvenueVancouver B.C. V6P 6P2CAFinsterwald, Martinet al00075232Manitz, Finsterwald & Partner GbR Martin-Greif-Strasse 180336 MünchenDEATBECHDEDKESFIFRGBGRIEITLILUMCNLPTSEUS199600994919960606enWO19960409641996121919965519970424000000