(19)
(11) EP 0 832 283 A2

(12)

(43) Date of publication:
01.04.1998 Bulletin 1998/14

(21) Application number: 96917145.0

(22) Date of filing: 06.06.1996
(51) International Patent Classification (IPC): 
C12Q 1/ 68( . )
(86) International application number:
PCT/US1996/008806
(87) International publication number:
WO 1996/041002 (19.12.1996 Gazette 1997/03)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 07.06.1995 US 19950487986
07.06.1995 US 19950488012
07.06.1995 US 19950488013
07.06.1995 US 19950487987

(71) Applicant: GENZYME CORPORATION
Framingham, Massachusetts 01701 (US)

(72) Inventor:
  • SHUBER, Anthony, P.
    Milford, MA 01757 (US)

(74) Representative: Cornish, Kristina Victoria Joy, et al 
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ
London WC1R 4PJ (GB)

   


(54) METHODS FOR THE IDENTIFICATION OF GENETIC MODIFICATION OF DNA INVOLVING DNA SEQUENCING AND POSITIONAL CLONING