(19)

(11)

EP 0 833 812 A1

(12)

(43) Date of publication: 08.04.1998 Bulletin 1998/15 (21) Application number: 96918775.0 (22) Date of filing: 21.06.1996

(51) International Patent Classification (IPC):  A61K 8/ 00( . ) A61K 8/ 36( . ) A61K 8/ 37( . ) A61K 8/ 49( . ) A61Q 5/ 02( . ) A61Q 5/ 12( . ) A61Q 19/ 08( . ) C07D 311/ 16( . ) C09B 67/ 00( . ) A61K 8/ 33( . ) A61K 8/ 368( . ) A61K 8/ 41( . ) A61Q 5/ 00( . ) A61Q 5/ 06( . ) A61Q 17/ 04( . ) C07C 69/ 734( . ) C08K 5/ 105( . ) C09K 3/ 00( . ) (86) International application number: PCT/GB1996/001481 (87) International publication number: WO 1997/000851 (09.01.1997 Gazette 1997/03)

(84) Designated Contracting States: CH DE FR GB LI (30) Priority: 23.06.1995 GB 19950012855 08.12.1995 GB 19950025162 (71) Applicant: ZYLEPSIS LIMITED Ashford, Kent TN24 8DH (GB)	(72) Inventors: CHEETHAM, Peter, Samuel, James Harrold, Bedfordshire MK43 7DR (GB) BANISTER, Nigel, Eric Canterbury, Kent CT1 2BZ (GB) (74) Representative: Bassett, Richard  ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate Nottingham NG1 1LE Nottingham NG1 1LE (GB)