IMMUNOCONJUGATES COMPRISING SINGLE-CHAIN VARIABLE REGION FRAGMENTS OF ANTI-CD-19 ANTIBODIES - Patent 0835134

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EP 0 835 134 A1

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(43)	Date of publication:
	15.04.1998 Bulletin 1998/16

(21)	Application number: 96916466.0

(22)	Date of filing: 15.05.1996

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61K 45/ 00^{( . )}
A61K 51/ 00^{( . )}
C07K 16/ 28^{( . )}
C12P 21/ 02^{( . )}
C12R 1/ 19^{( . )}

A61K 38/ 46^{( . )}
A61K 47/ 48^{( . )}
A61P 35/ 00^{( . )}
C07K 16/ 30^{( . )}
A61K 38/ 00^{( . )}

(86)	International application number:
	PCT/US1996/006941

(87)	International publication number:
	WO 1996/036360 (21.11.1996 Gazette 1996/51)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

17.05.1995 US 19950443408

(71)	Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
	Minneapolis MN 55455 (US)

(72)	Inventors:
	KERSEY, John, H., Jr. Saint Paul, MN 55108 (US) BEJCEK, Bruce, E. Portage, MI 49002 (US) WANG, Duo Plymouth, MN 55442 (US) UCKUN, Fatih, M. White Bear Lake, MN 55110 (US)

(74)	Representative: Kolb, Helga, Dr. Dipl.-Chem., et al
	Hoffmann Eitle, Patent- und Rechtsanwälte, Arabellastrasse 4 81925 München 81925 München (DE)

(54)	IMMUNOCONJUGATES COMPRISING SINGLE-CHAIN VARIABLE REGION FRAGMENTS OF ANTI-CD-19 ANTIBODIES