COMBINATIONS OF INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - Patent 0836383

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EP 0 836 383 A1

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(43)	Date of publication:
	22.04.1998 Bulletin 1998/17

(21)	Application number: 96923503.0

(22)	Date of filing: 26.06.1996

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International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61K 31/ 202^{( . )}
A61K 31/ 223^{( . )}
A61K 31/ 415^{( . )}
A61K 31/ 425^{( . )}
A61K 31/ 495^{( . )}
A61K 31/ 662^{( . )}
A61K 38/ 03^{( . )}
A61K 45/ 06^{( . )}
A61P 43/ 00^{( . )}

A61K 31/ 20^{( . )}
A61K 31/ 22^{( . )}
A61K 31/ 255^{( . )}
A61K 31/ 4164^{( . )}
A61K 31/ 428^{( . )}
A61K 31/ 66^{( . )}
A61K 31/ 664^{( . )}
A61K 38/ 55^{( . )}
A61P 35/ 00^{( . )}

(86)	International application number:
	PCT/US1996/011022

(87)	International publication number:
	WO 1997/001275 (16.01.1997 Gazette 1997/04)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

29.06.1995 US 19950002251P
14.02.1996 GB 19960003091

(71)	Applicants:
	MERCK & CO., INC. Rahway, New Jersey 07065 (US) BANYU PHARMACEUTICAL CO., LTD. Chuo-ku Tokyo 103 (JP)

(72)	Inventors:
	CASKEY, Charles, T. Rahway, NJ 07065 (US) NISHIMURA, Susumu Chuo-ku, Tokyo 103 (JP) YONEMOTO, Mari Chuo-ku, Tokyo 103 (JP)

(74)	Representative: Thompson, John Dr., et al
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	COMBINATIONS OF INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE