(19)

(11)

EP 0 836 478 A1

(12)

(43) Date of publication: 22.04.1998 Bulletin 1998/17 (21) Application number: 96922041.0 (22) Date of filing: 27.06.1996

(51) International Patent Classification (IPC):  A61K 35/ 64( . ) A61K 36/ 32( . ) A61K 36/ 328( . ) A61K 36/ 00( . ) A61K 36/ 324( . ) (86) International application number: PCT/EP1996/002824 (87) International publication number: WO 1997/002040 (23.01.1997 Gazette 1997/05)

(84) Designated Contracting States: AT DE ES FR GB IT NL SE (30) Priority: 03.07.1995 IT 1995PD00133 03.07.1995 IT 1995PD00134 20.02.1996 IT 1996PD00038 (71) Applicants: Bevilacqua, Maria 35128 Padova (IT) Michelin Lausarot, Elisa 10090 Villarbasse (IT)	(72) Inventors: BEVILACQUA, Matteo I-35128 Padova (IT) ZACCAGNA, Carlo, Alberto I-10090 Villarbasse (IT) (74) Representative: Modiano, Guido, Dr.-Ing., et al  Modiano & Associati S.r.l. Via Meravigli, 16 20123 Milano 20123 Milano (IT)