(19)

(11)

EP 0 837 882 A1

(12)

(43) Date of publication: 29.04.1998 Bulletin 1998/18 (21) Application number: 96920798.0 (22) Date of filing: 06.06.1996

(51) International Patent Classification (IPC):  A61K 47/ 42( . ) C07K 1/ 02( . ) G01N 30/ 26( . ) G01N 33/ 531( . ) B01J 20/ 281( . ) C07K 14/ 78( . ) G01N 30/ 88( . ) G01N 33/ 543( . ) (86) International application number: PCT/EP1996/002453 (87) International publication number: WO 1996/041817 (27.12.1996 Gazette 1997/04)

(84) Designated Contracting States: AT DE FR GB (30) Priority: 10.06.1995 EP 19950108967 (71) Applicant: Pentapharm A.G. CH-4052 Basel (CH)	(72) Inventors: STOCKER, Kurt CH-4147 Aesch (CH) GAFFNEY, Patrick, J. Herts AL5 5LA (GB) (74) Representative: Braun, André  BRAUN & PARTNER Patent-, Marken-, Rechtsanwälte Reussstrasse 22 4054 Basel 4054 Basel (CH)