(19)

(11)

EP 0 839 047 A1

(12)

(43) Date of publication: 06.05.1998 Bulletin 1998/19 (21) Application number: 96923034.0 (22) Date of filing: 16.07.1996

(51) International Patent Classification (IPC):  A61K 9/ 50( . ) A61K 38/ 28( . ) A61K 47/ 46( . ) A61K 38/ 26( . ) A61K 47/ 18( . ) (86) International application number: PCT/IL1996/000055 (87) International publication number: WO 1997/003688 (06.02.1997 Gazette 1997/07)

(84) Designated Contracting States: CH DE DK ES FR GB IT LI NL SE (30) Priority: 19.07.1995 IL 19950114673 (71) Applicant: HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT CO. LTD. Jerusalem 91120 (IL)	(72) Inventors: KIDRON, Miriam 97366 Jerusalem (IL) ZIV, Ehud 90820 Motza Elit (IL) BAR-ON, Hanoch 93784 Jerusalem (IL) (74) Representative: Modiano, Guido, Dr.-Ing., et al  Modiano, Josif, Pisanty & Staub, Baaderstrasse 3 80469 München 80469 München (DE)