TRIBENZIMIDAZOLES USEFUL AS TOPOISOMERASE I INHIBITORS - Patent 0839140

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EP 0 839 140 A1

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(43)	Date of publication:
	06.05.1998 Bulletin 1998/19

(21)	Application number: 96915784.0

(22)	Date of filing: 14.05.1996

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International Patent Classification (IPC):

C07D 235/ 20^{( . )}
A61K 31/ 4184^{( . )}
C07D 235/ 18^{( . )}

A61K 31/ 415^{( . )}
A61P 35/ 00^{( . )}
C07D 401/ 14^{( . )}

(86)	International application number:
	PCT/US1996/006853

(87)	International publication number:
	WO 1996/036612 (21.11.1996 Gazette 1996/51)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV SI

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Priority:

17.05.1995 US 19950442657
20.03.1996 US 19960618988

(71)	Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
	New Brunswick, NJ 08903 (US)

(72)	Inventors:
	LAVOIE, Edmond, J. Princeton Junction, NJ 08550 (US) LIU, Leroy, Fong Bridgewater, NJ 08807 (US) SUN, Qun Zheijiang 311200 (CN)

(74)	Representative: Calamita, Roberto
	Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)

(54)	TRIBENZIMIDAZOLES USEFUL AS TOPOISOMERASE I INHIBITORS