(19)

(11)

EP 0 840 600 A1

(12)

(43) Date of publication: 13.05.1998 Bulletin 1998/20 (21) Application number: 96927180.0 (22) Date of filing: 26.07.1996

(51) International Patent Classification (IPC):  A61K 9/ 70( . ) A61K 31/ 612( . ) A61K 47/ 30( . ) A61K 31/ 60( . ) A61K 31/ 616( . ) (86) International application number: PCT/IE1996/000049 (87) International publication number: WO 1997/004759 (13.02.1997 Gazette 1997/08)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 27.07.1995 IE 19950000575 27.05.1996 IE 19960000368 (71) Applicant: CAL INTERNATIONAL LIMITED Mount Merrion, County Dublin (IE)	(72) Inventors: BYRNE, William County Dublin (IE) McCAFFERTY, Dermot Belfast BT8 4YR (GB) (74) Representative: O'Brien, John Augustine, et al  John A. O'Brien & Associates, Third Floor, Duncairn House, 14 Carysfort Avenue Blackrock, Co Dublin Blackrock, Co Dublin (IE)