(19)

(11)

EP 0 840 790 A1

(12)

(43) Date of publication: 13.05.1998 Bulletin 1998/20 (21) Application number: 96926383.0 (22) Date of filing: 18.07.1996

(51) International Patent Classification (IPC):  A23J 1/ 00( . ) C12N 15/ 56( . ) C12P 19/ 14( . ) C12N 9/ 24( . ) C12P 17/ 18( . ) (86) International application number: PCT/EP1996/003232 (87) International publication number: WO 1997/004107 (06.02.1997 Gazette 1997/07)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 18.07.1995 EP 19950201980 (71) Applicant: GIST-BROCADES B.V. NL-2600 MA Delft (NL)	(72) Inventors: EDENS, Luppo NL-3062 JL Rotterdam (NL) SOUPPE, Jérôme F-59290 Wasquehal (FR) SCHIPPER, Dirk NL-2612 HL Delft (NL) NAN, Helena, Maria NL-2631 JR Nootdorp (NL) (74) Representative: Klein, Bart  Gist-Brocades, Patents Trademarks Department, Wateringseweg 1, P.O. Box 1 2600 MA Delft 2600 MA Delft (NL)