(19)

(11)

EP 0 845 975 A1

(12)

(43) Date of publication: 10.06.1998 Bulletin 1998/24 (21) Application number: 96940622.0 (22) Date of filing: 22.08.1996

(51) International Patent Classification (IPC):  A61K 8/ 00( . ) A61K 8/ 40( . ) A61K 8/ 89( . ) A61Q 5/ 00( . ) C08L 83/ 04( . ) A61K 8/ 34( . ) A61K 8/ 41( . ) A61K 8/ 891( . ) A61Q 5/ 12( . ) (86) International application number: PCT/US1996/013561 (87) International publication number: WO 1997/007774 (06.03.1997 Gazette 1997/11)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE (30) Priority: 23.08.1995 AU 1995PN04998 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati, Ohio 45202 (US)	(72) Inventor: NAKAMURA, Kiichiro Kobe 658 (JP) (74) Representative: Woof, Victoria, et al  Procter & Gamble Pharmaceuticals Ltd., Patent Department, Lovett House, Lovett Road Staines, Middlesex TW18 3AZ Staines, Middlesex TW18 3AZ (GB)