(19)

(11)

EP 0 850 060 A1

(12)

(43) Date of publication: 01.07.1998 Bulletin 1998/27 (21) Application number: 96923020.0 (22) Date of filing: 29.07.1996

(51) International Patent Classification (IPC):  A61K 31/ 435( . ) A61P 31/ 04( . ) A61K 31/ 4375( . ) C07D 471/ 04( . ) (86) International application number: PCT/IB1996/000756 (87) International publication number: WO 1997/007800 (06.03.1997 Gazette 1997/11)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE Designated Extension States: SI (30) Priority: 29.08.1995 US 19950002975 (71) Applicant: PFIZER INC. New York, N.Y. 10017 (US)	(72) Inventors: ALLEN, Douglas, John, Meldrum New London, CT 06320 (US) JOSEPH, David, Bruning New London, CT 06320 (US) NORRIS, Timothy Gales Ferry, CT 06335 (US) (74) Representative: Wood, David John, et al  PFIZER LIMITED, European Patents Department, Ramsgate Road, Sandwich, Kent CT13 9NJ Sandwich, Kent CT13 9NJ (GB)