(19)
(11) EP 0 850 066 A1

(12)

(43) Date of publication:
01.07.1998 Bulletin 1998/27

(21) Application number: 96925359.0

(22) Date of filing: 19.07.1996
(51) International Patent Classification (IPC): 
A61K 31/ 00( . )
C07K 14/ 47( . )
A61K 41/ 00( . )
(86) International application number:
PCT/US1996/011886
(87) International publication number:
WO 1997/003681 (06.02.1997 Gazette 1997/07)
(84) Designated Contracting States:
DE FR GB IT

(30) Priority: 20.07.1995 US 19950001248

(71) Applicant: WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH, INC.
Shrewsbury, MA 01545-8000 (US)

(72) Inventors:
  • ROSS, Alonzo, H.
    Shrewsbury, MA 01545 (US)
  • POLUHA, Wojciech
    Shrewsbury, MA 01545 (US)
  • POLUHA, Dorota, K.
    Shrewsbury, MA 01545 (US)

(74) Representative: Jump, Timothy John Simon, et al 
Venner Shipley & Co. 20 Little Britain
London EC1A 7DH
London EC1A 7DH (GB)

   


(54) METHODS FOR SELECTIVELY KILLING OR INHIBITING THE GROWTH OF CELLS EXPRESSING THE WAF1 GENE