UBIQUITIN CONJUGATING ENZYMES HAVING TRANSCRIPTIONAL REPRESSOR ACTIVITY

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EP 0 850 250 A1

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(43)	Date of publication:
	01.07.1998 Bulletin 1998/27

(21)	Application number: 96929829.0

(22)	Date of filing: 30.08.1996

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61K 38/ 43^{( . )}
A61P 35/ 00^{( . )}
C07K 14/ 47^{( . )}
C12N 1/ 15^{( . )}
C12N 1/ 21^{( . )}
C12N 9/ 00^{( . )}

A61K 38/ 00^{( . )}
A61K 48/ 00^{( . )}
A61P 43/ 00^{( . )}
C07K 19/ 00^{( . )}
C12N 1/ 19^{( . )}
C12N 5/ 10^{( . )}
C12N 15/ 63^{( . )}

(86)	International application number:
	PCT/US1996/014013

(87)	International publication number:
	WO 1997/008195 (06.03.1997 Gazette 1997/11)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

30.08.1995 US 19950002995
21.05.1996 US 19960018040

(71)	Applicants:
	Barnes-Jewish Hospital D/B/A St. Louis, MO 63178 (US) TRUSTEES OF PRINCETON UNIVERSITY Princeton, NJ 08544-0036 (US)

(72)	Inventors:
	DEUEL, Thomas, F. Cambridge, MA 02138 (US) SHENK, Thomas Princeton, NY 08540 (US) WANG, Zhao-Yi Millford, CT 06460 (US)

(74)	Representative: Brand, Thomas Louis
	W.P. Thompson & Co., Celcon House, 289-293 High Holborn London WC1V 7HU London WC1V 7HU (GB)

(54)	UBIQUITIN CONJUGATING ENZYMES HAVING TRANSCRIPTIONAL REPRESSOR ACTIVITY