(19)

(11)

EP 0 850 317 A1

(12)

(43) Date of publication: 01.07.1998 Bulletin 1998/27 (21) Application number: 96928620.0 (22) Date of filing: 02.09.1996

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C12Q 1/ 68( . ) (86) International application number: PCT/GB1996/002136 (87) International publication number: WO 1997/009449 (13.03.1997 Gazette 1997/12)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 02.09.1995 GB 19950017914 (71) Applicant: TEPNEL MEDICAL LIMITED Knutsford, Cheshire WA16 9PD (GB)	(72) Inventor: MINTER, Stephen Oven Hill Road New Mills SK12 4QL (GB) (74) Representative: Atkinson, Peter Birch, et al  MARKS & CLERK, Sussex House, 83-85 Mosley Street Manchester M2 3LG Manchester M2 3LG (GB)