(19)

(11)

EP 0 851 917 A1

(12)

(43) Date of publication: 08.07.1998 Bulletin 1998/28 (21) Application number: 96927924.0 (22) Date of filing: 23.08.1996

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C12N 5/ 10( . ) C12P 21/ 02( . ) C07K 14/ 505( . ) C12N 15/ 85( . ) C12R 1/ 91( . ) (86) International application number: PCT/KR1996/000145 (87) International publication number: WO 1997/008307 (06.03.1997 Gazette 1997/11)

(84) Designated Contracting States: CH DE ES FR GB IT LI SE (30) Priority: 24.08.1995 KR 19950026391 (71) Applicant: IL-DONG PHARM. CO., LTD. Seoul 137-130 (KR)

(72) Inventors: KIM, Sun, Young Seocho-ku, Seoul 137-040 (KR) KIM, Kee, Won Kangnam-ku, Seoul 135-110 (KR) KIM, Tae, Han Seongnam-shi, Kyonggi-do 463-010 (KR) HWANG, Jeong, Ho Seognam-shi, Kyonggi-do 463-060 (KR) KIM, Seon, Hee Seocho-ku, Seoul 137-042 (KR) LEE, Sun, Young Songpa-ku, Seoul 138-160 (KR) (74) Representative: Bassett, Richard Simon  Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)