(19)
(11) EP 0 851 931 A1

(12)

(43) Date of publication:
08.07.1998 Bulletin 1998/28

(21) Application number: 96933358.0

(22) Date of filing: 23.09.1996
(51) International Patent Classification (IPC): 
A23L 1/ 03( . )
C07K 14/ 36( . )
C07K 14/ 535( . )
C07K 14/ 55( . )
C07K 14/ 81( . )
C12N 1/ 21( . )
C12N 15/ 31( . )
C12N 15/ 76( . )
A61K 38/ 00( . )
 A61K 38/ 55( . )
C07K 14/ 525( . )
C07K 14/ 54( . )
C07K 14/ 76( . )
C07K 19/ 00( . )
C12N 15/ 11( . )
C12N 15/ 62( . )
C12Q 1/ 68( . )
(86) International application number:
PCT/EP1996/004146
(87) International publication number:
WO 1997/011187 (27.03.1997 Gazette 1997/14)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV SI

(30) Priority: 22.09.1995 EP 19950870106

(71) Applicant: INNOGENETICS N.V.
9052 Gent (BE)

(72) Inventors:
  • ANNE, Jozef
    B-3020 Winksele-Herent (BE)
  • VAN MELLAERT, Lieve
    B-2820 Bonheiden (BE)
  • LAMMERTYN, Elke
    B-3000 Leuven (BE)
  • SCARCEZ, Thierry-Eurogen. S.A.-Molec. Biol. Div.
    B-4102 Seraing (BE)
  • VAN BROEKHOVEN, Annie
    B-2600 Berchem (BE)

(74) Representative: De Clercq, Ann G. Y. 
Innogenetics N.V., Industriepark Zwijnaarde 7, P.O. Box 4
9052 Gent
9052 Gent (BE)

   


(54) SUBTILISIN INHIBITOR OF STREPTOMYCES VENEZUELAE, AND USE OF THE GENE SEQUENCES FOR EXPRESSION AND/OR SECRETION OF HETEROLOGOUS PROTEINS IN STREPTOMYCES