(19)
(11) EP 0 854 913 A1

(12)

(43) Date of publication:
29.07.1998 Bulletin 1998/31

(21) Application number: 96933226.0

(22) Date of filing: 02.10.1996
(51) International Patent Classification (IPC): 
C12M 3/ 08( . )
C12N 7/ 02( . )
C12N 1/ 06( . )
(86) International application number:
PCT/US1996/015801
(87) International publication number:
WO 1997/012959 (10.04.1997 Gazette 1997/16)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 06.10.1995 US 19950605062
22.02.1996 GB 19960003759

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • SEIFERT, Douglas, B.
    Rahway, NJ 07065 (US)
  • LEU, Frank, S.
    Rahway, NJ 07065 (US)

(74) Representative: Thompson, John Dr., et al 
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) METHOD OF DISRUPTING CULTURED CELLS USING AN IMPINGING JET DEVICE