CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS - Patent 0858444

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(11)

EP 0 858 444 A1

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(43)	Date of publication:
	19.08.1998 Bulletin 1998/34

(21)	Application number: 96941315.0

(22)	Date of filing: 15.10.1996

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International Patent Classification (IPC):

A61K 31/ 16^{( . )}
A61K 31/ 34^{( . )}
A61K 31/ 381^{( . )}
A61K 31/ 4015^{( . )}
A61K 31/ 41^{( . )}
A61K 31/ 4178^{( . )}
A61K 31/ 42^{( . )}
A61K 31/ 4245^{( . )}
A61K 31/ 426^{( . )}
A61K 31/ 428^{( . )}
A61K 31/ 44^{( . )}
A61K 31/ 4406^{( . )}
A61K 31/ 4439^{( . )}
A61K 31/ 47^{( . )}
A61K 31/ 5375^{( . )}
A61P 1/ 08^{( . )}
A61P 25/ 06^{( . )}
A61P 43/ 00^{( . )}
C07C 43/ 196^{( . )}
C07C 62/ 38^{( . )}
C07C 217/ 52^{( . )}
C07C 233/ 81^{( . )}
C07C 265/ 10^{( . )}
C07C 275/ 26^{( . )}
C07D 207/ 26^{( . )}
C07D 209/ 08^{( . )}
C07D 211/ 16^{( . )}
C07D 211/ 62^{( . )}
C07D 213/ 38^{( . )}
C07D 215/ 18^{( . )}
C07D 233/ 32^{( . )}
C07D 233/ 70^{( . )}
C07D 239/ 26^{( . )}
C07D 249/ 12^{( . )}
C07D 261/ 08^{( . )}
C07D 271/ 06^{( . )}
C07D 277/ 28^{( . )}
C07D 295/ 08^{( . )}
C07D 295/ 18^{( . )}
C07D 307/ 52^{( . )}
C07D 307/ 79^{( . )}
C07D 307/ 92^{( . )}
C07D 333/ 32^{( . )}
C07D 333/ 58^{( . )}
C07D 403/ 10^{( . )}
C07D 405/ 12^{( . )}
C07D 413/ 12^{( . )}
C07D 417/ 10^{( . )}
C07D 513/ 04^{( . )}
C07J 73/ 00^{( . )}

A61K 31/ 215^{( . )}
A61K 31/ 343^{( . )}
A61K 31/ 40^{( . )}
A61K 31/ 404^{( . )}
A61K 31/ 4166^{( . )}
A61K 31/ 4192^{( . )}
A61K 31/ 421^{( . )}
A61K 31/ 425^{( . )}
A61K 31/ 427^{( . )}
A61K 31/ 429^{( . )}
A61K 31/ 4402^{( . )}
A61K 31/ 4409^{( . )}
A61K 31/ 445^{( . )}
A61K 31/ 505^{( . )}
A61K 31/ 5377^{( . )}
A61P 11/ 06^{( . )}
A61P 29/ 00^{( . )}
C07C 43/ 192^{( . )}
C07C 62/ 32^{( . )}
C07C 69/ 757^{( . )}
C07C 229/ 48^{( . )}
C07C 237/ 06^{( . )}
C07C 271/ 24^{( . )}
C07D 207/ 16^{( . )}
C07D 207/ 38^{( . )}
C07D 211/ 14^{( . )}
C07D 211/ 58^{( . )}
C07D 213/ 30^{( . )}
C07D 213/ 61^{( . )}
C07D 215/ 20^{( . )}
C07D 233/ 61^{( . )}
C07D 233/ 86^{( . )}
C07D 249/ 08^{( . )}
C07D 257/ 04^{( . )}
C07D 263/ 32^{( . )}
C07D 271/ 10^{( . )}
C07D 277/ 64^{( . )}
C07D 295/ 12^{( . )}
C07D 307/ 42^{( . )}
C07D 307/ 64^{( . )}
C07D 307/ 82^{( . )}
C07D 333/ 20^{( . )}
C07D 333/ 38^{( . )}
C07D 401/ 04^{( . )}
C07D 403/ 12^{( . )}
C07D 413/ 10^{( . )}
C07D 417/ 04^{( . )}
C07D 417/ 12^{( . )}
C07D 521/ 00^{( . )}

(86)	International application number:
	PCT/US1996/016489

(87)	International publication number:
	WO 1997/014671 (24.04.1997 Gazette 1997/18)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

18.10.1995 US 19950005558P
13.02.1996 GB 19960002853

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

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Inventors:

FINKE, Paul, E.
Rahway, NJ 07065 (US)
MacCOSS, Malcom
Rahway, NJ 07065 (US)
MEURER, Laura, C.
Rahway, NJ 07065 (US)
MILLS, Sander, G.
Rahway, NJ 07065 (US)
CALDWELL, Charles, G.
Rahway, NJ 07065 (US)
CHEN, Ping
Rahway, NJ 07065 (US)
DURETTE, Philippe, L.
Rahway, NJ 07065 (US)
HALE, Jeffery
Rahway, NJ 07065 (US)
HOLSON, Edward
Rahway, NJ 07065 (US)
KOPKA, Ihor
Rahway, NJ 07065 (US)
ROBICHAUD, Albert
Rahway, NJ 07065 (US)

(74)	Representative: Hiscock, Ian James, et al
	European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	CYCLOPENTYL TACHYKININ RECEPTOR ANTAGONISTS