(19)

(11)

EP 0 859 586 A1

(12)

(43) Date of publication: 26.08.1998 Bulletin 1998/35 (21) Application number: 97907909.0 (22) Date of filing: 27.02.1997

(51) International Patent Classification (IPC):  A61K 8/ 34( . ) A61K 8/ 44( . ) A61K 8/ 42( . ) A61Q 5/ 12( . ) (86) International application number: PCT/US1997/003066 (87) International publication number: WO 1997/031616 (04.09.1997 Gazette 1997/38)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE (30) Priority: 28.02.1996 AU 19960045808 08.11.1996 WO 1996US18011 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati, Ohio 45202 (US)	(72) Inventors: MITSUMATSU, Arata Hyogo 659 (JP) NAKAMURA, Kiichiro Higashinada-ku, Kobe 658 (JP) YOKOGI, Junichi Higashinada-ku, Kobe 658 (JP) (74) Representative: Woof, Victoria, et al  Procter & Gamble Technical Centres Ltd, Patent Department, Lovett House, Lovett Road Staines, Middlesex TW18 3AZ Staines, Middlesex TW18 3AZ (GB)