(19)

(11)

EP 0 859 598 A1

(12)

(43) Date of publication: 26.08.1998 Bulletin 1998/35 (21) Application number: 96900365.0 (22) Date of filing: 17.01.1996

(51) International Patent Classification (IPC):  A61K 9/ 127( . ) A61K 47/ 24( . ) A61K 31/ 56( . ) A61K 9/ 00( . ) (86) International application number: PCT/GB1996/000083 (87) International publication number: WO 1996/022764 (01.08.1996 Gazette 1996/35)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE (30) Priority: 24.01.1995 GB 19950001286 (71) Applicant: Novartis AG 4058 Basel (CH)	(72) Inventors: TAYLOR, Peter, William Billingshurst West Sussex RH14 9HF (GB) MAAS, Janet, Catherine West Sussex RH13 5DB (GB)