(19)

(11)

EP 0 859 839 A1

(12)

(43) Date of publication: 26.08.1998 Bulletin 1998/35 (21) Application number: 96935079.0 (22) Date of filing: 21.10.1996

(51) International Patent Classification (IPC):  C07K 14/ 47( . ) C12N 15/ 12( . ) C07K 16/ 18( . ) A61K 38/ 00( . ) (86) International application number: PCT/GB1996/002605 (87) International publication number: WO 1997/014794 (24.04.1997 Gazette 1997/18)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 20.10.1995 GB 19950021544 (71) Applicant: UNIVERSITY OF DUNDEE Dundee DD1 4HN (GB)	(72) Inventors: LANE, David Philip, Magicwell House Balmullo Fife KY16 O8N (GB) HUPP, Theodore, Robert Dundee DD2 1PA (GB) (74) Representative: Kiddle, Simon John, et al  Mewburn Ellis, York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)