(19)

(11)

EP 0 861 086 A1

(12)

(43) Date of publication: 02.09.1998 Bulletin 1998/36 (21) Application number: 96939682.0 (22) Date of filing: 13.11.1996

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) A61K 38/ 17( . ) C07K 14/ 78( . ) C12P 21/ 02( . ) A61K 38/ 00( . ) A61P 43/ 00( . ) C07K 19/ 00( . ) (86) International application number: PCT/US1996/018149 (87) International publication number: WO 1997/017988 (22.05.1997 Gazette 1997/22)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 13.11.1995 US P 6608 12.11.1996 US A 745539 (71) Applicant: FIBROGEN, INC. South San Francisco, CA 94080 (US)	(72) Inventors: VUORIO, Eero FIN-20610 Turko (FI) MARTIN, George Palo Alto, CA 94301 (US) NEFF, Thomas, B. Atherton, CA 94025 (US) ALA-KOKKO, Leena FIN-90220 Oulu (FI) (74) Representative: Schüssler, Andrea, Dr., et al  Kanzlei Huber & Schüssler Truderinger Strasse 246 81825 München 81825 München (DE)