INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - Patent 0862435

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(11)

EP 0 862 435 A1

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(43)	Date of publication:
	09.09.1998 Bulletin 1998/37

(21)	Application number: 96942798.0

(22)	Date of filing: 18.11.1996

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International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61K 31/ 445^{( . )}
A61K 31/ 4523^{( . )}
A61K 31/ 535^{( . )}
A61K 31/ 5377^{( . )}
A61P 13/ 00^{( . )}
A61P 27/ 00^{( . )}
A61P 31/ 00^{( . )}
A61P 35/ 00^{( . )}
C07D 233/ 24^{( . )}

A61K 31/ 4427^{( . )}
A61K 31/ 4465^{( . )}
A61K 31/ 454^{( . )}
A61K 31/ 5375^{( . )}
A61P 9/ 00^{( . )}
A61P 13/ 12^{( . )}
A61P 27/ 02^{( . )}
A61P 31/ 12^{( . )}
A61P 43/ 00^{( . )}
C07D 401/ 12^{( . )}

(86)	International application number:
	PCT/US1996/018811

(87)	International publication number:
	WO 1997/018813 (29.05.1997 Gazette 1997/23)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

22.11.1995 US 19950007498P
29.02.1996 GB 19960004311

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	KIM, Byeong, M. Rahway, NJ 07065 (US) SHAW, Anthony, W. Rahway, NJ 07065 (US) GRAHAM, Samuel, L. Rahway, NJ 07065 (US) deSOLMS, S., Jane Rahway, NJ 07065 (US) CICCARONE, Terrence, M. Rahway, NJ 07065 (US)

(74)	Representative: Thompson, John Dr.
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE