(19)

(11)

EP 0 862 626 A1

(12)

(43) Date of publication: 09.09.1998 Bulletin 1998/37 (21) Application number: 96932384.0 (22) Date of filing: 09.10.1996

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) A61K 38/ 00( . ) A61P 9/ 12( . ) C07K 14/ 435( . ) C12N 15/ 12( . ) A61K 31/ 00( . ) A61P 9/ 00( . ) A61P 35/ 00( . ) C12N 1/ 21( . ) (86) International application number: PCT/AU1996/000632 (87) International publication number: WO 1997/013854 (17.04.1997 Gazette 1997/17)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 09.10.1995 AU 1995PN05839 (71) Applicant: NORTHERN SYDNEY AREA HEALTH SERVICE St. Leonards, NSW 2065 (AU)	(72) Inventors: DONOVAN, Gregory Berowra Heights, NWS 2082 (AU) BALDO, Brian Pymble, NWS 2073 (AU) (74) Representative: Perry, Robert Edward  GILL JENNINGS & EVERY Broadgate House 7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)