(19)
(11) EP 0 863 917 A1

(12)

(43) Date of publication:
16.09.1998 Bulletin 1998/38

(21) Application number: 96938216.0

(22) Date of filing: 14.11.1996
(51) International Patent Classification (IPC): 
C07H( . )
A61K 31/ 00( . )
A61K 31/ 7028( . )
A61K 31/ 704( . )
A61K 47/ 48( . )
C07B 43/ 00( . )
C07K 7/ 23( . )
C07H 15/ 252( . )
A61K 31/ 70( . )
A61K 31/ 7034( . )
A61K 38/ 00( . )
A61P 35/ 00( . )
C07B 61/ 00( . )
(86) International application number:
PCT/EP1996/005029
(87) International publication number:
WO 1997/019954 (05.06.1997 Gazette 1997/24)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 27.11.1995 US 19950562652

(60) Divisional application:
03010988.8 / 1384710

(71) Applicant: ASTA Medica Aktiengesellschaft
D-01277 Dresden (DE)

(72) Inventors:
  • SCHALLY, Andrew V., Tulane University Med. Ctr
    New Orleans, LA 70112-2699 (US)
  • NAGY, Attila A., Tulane University Med. Ctr
    New Orleans, LA 70112-2699 (US)
  • CAI, Ren-Zhi, Tulane University Med. Ctr
    New Orleans, LA 70112-2699 (US)

(74) Representative: Sander, Uwe 
c/o ASTA MEDICA AKTIENGESELLSCHAFT, Meissner Strasse 35
01435 Radebeul
01435 Radebeul (DE)

   


(54) TARGETED CYTOTOXIC ANTHRACYCLINE ANALOGS