(19)

(11)

EP 0 865 298 A1

(12)

(43) Date of publication: 23.09.1998 Bulletin 1998/39 (21) Application number: 96940685.0 (22) Date of filing: 06.12.1996

(51) International Patent Classification (IPC):  A61K 31/ 00( . ) A61K 38/ 43( . ) A61K 45/ 00( . ) A61P 35/ 00( . ) C07C 333/ 04( . ) C07D 239/ 38( . ) A61K 31/ 505( . ) A61K 39/ 395( . ) A61K 47/ 48( . ) A61P 43/ 00( . ) C07D 213/ 72( . ) (86) International application number: PCT/GB1996/003000 (87) International publication number: WO 1997/020580 (12.06.1997 Gazette 1997/25)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 06.12.1995 GB 19950024942 (71) Applicant: AEPACT Limited London WC1E 6HQ (GB)	(72) Inventor: KHAN, Tariq Herts CM23 3DP (GB) (74) Representative: Bassett, Richard Simon, et al  Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)