(19)
(11) EP 0 865 429 A1

(12)

(43) Date of publication:
23.09.1998 Bulletin 1998/39

(21) Application number: 96942375.0

(22) Date of filing: 04.12.1996
(51) International Patent Classification (IPC): 
A61K 31/ 00( . )
A61K 31/ 397( . )
A61K 31/ 422( . )
A61K 31/ 427( . )
A61K 31/ 4427( . )
A61P 3/ 10( . )
A61P 9/ 10( . )
A61P 17/ 06( . )
A61P 25/ 04( . )
A61P 43/ 00( . )
C07D 401/ 12( . )
C07D 413/ 06( . )
C07D 417/ 06( . )
A61K 31/ 395( . )
A61K 31/ 42( . )
A61K 31/ 425( . )
A61K 31/ 44( . )
A61P 3/ 00( . )
A61P 9/ 00( . )
A61P 17/ 00( . )
A61P 25/ 00( . )
A61P 29/ 00( . )
C07D 205/ 09( . )
C07D 401/ 14( . )
C07D 413/ 12( . )
C07D 417/ 12( . )
(86) International application number:
PCT/EP1996/005588
(87) International publication number:
WO 1997/021676 (19.06.1997 Gazette 1997/26)
(84) Designated Contracting States:
BE CH DE ES FR GB IT LI NL

(30) Priority: 08.12.1995 GB 19950025148
08.12.1995 GB 19950025149
08.12.1995 GB 19950025150

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford, Middlesex TW8 9EP (GB)

(72) Inventors:
  • HICKEY, Deirdre, Mary, Bernadette
    Harlow, Essex CM19 5AW (GB)
  • DHANAK, Dashyant
    Collegeville, PA 19426-0989 (US)
  • IFE, Robert, John
    Harlow, Essex CM19 5AW (GB)
  • LEACH, Colin, Andrew
    Harlow, Essex CM19 5AW (GB)
  • TEW, David, Graham
    Hertfordshire AL6 9AR (GB)

(74) Representative: Connell, Anthony Christopher, et al 
SmithKline Beecham plc Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) AZETIDINONE COMPOUNDS FOR THE TREATMENT OF ATHEROSCLEROSIS