(19)
(11) EP 0 866 799 A1

(12)

(43) Date of publication:
30.09.1998 Bulletin 1998/40

(21) Application number: 96937887.0

(22) Date of filing: 31.10.1996
(51) International Patent Classification (IPC): 
A01K 67/ 027( . )
C12N 5/ 00( . )
C12N 15/ 09( . )
C12R 1/ 91( . )
C07K 14/ 775( . )
C12N 5/ 10( . )
A61K 38/ 00( . )
(86) International application number:
PCT/US1996/017629
(87) International publication number:
WO 1997/016458 (09.05.1997 Gazette 1997/20)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 01.11.1995 US 19950551722

(71) Applicants:
  • KOS PHARMACEUTICALS, INC.
    Miami, FL 33131 (US)
  • TRUSTEES OF BOSTON UNIVERSITY
    Boston, MA 02215 (US)

(72) Inventors:
  • ZANNIS, Vassilis I.
    Newton, MA 02159 (US)
  • ALESHKOV, Sergie B.
    Allston, MA 02134 (US)

(74) Representative: Vossius, Volker, Dr., et al 
Dr. Volker Vossius, Patentanwaltskanzlei - Rechtsanwaltskanzlei, Holbeinstrasse 5
81679 München
81679 München (DE)

   


(54) APOLIPOPROTEIN E2 AND TREATMENT OF ALZHEIMER'S DISEASE