ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE - Patent 0868178

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EP 0 868 178 A1

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(43)	Date of publication:
	07.10.1998 Bulletin 1998/41

(21)	Application number: 96943763.0

(22)	Date of filing: 10.12.1996

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International Patent Classification (IPC):

C07D 401/ 06^{( . )}
A61K 31/ 403^{( . )}
A61K 31/ 4045^{( . )}
A61K 31/ 4427^{( . )}
A61K 31/ 445^{( . )}
A61K 31/ 495^{( . )}
A61P 1/ 00^{( . )}
A61P 5/ 00^{( . )}
A61P 5/ 24^{( . )}
A61P 13/ 02^{( . )}
A61P 15/ 16^{( . )}
A61P 17/ 00^{( . )}
A61P 29/ 00^{( . )}
A61P 37/ 00^{( . )}
C07D 209/ 16^{( . )}
C07D 403/ 04^{( . )}

A61K 31/ 40^{( . )}
A61K 31/ 404^{( . )}
A61K 31/ 437^{( . )}
A61K 31/ 4439^{( . )}
A61K 31/ 454^{( . )}
A61K 31/ 496^{( . )}
A61P 1/ 06^{( . )}
A61P 5/ 02^{( . )}
A61P 11/ 16^{( . )}
A61P 15/ 00^{( . )}
A61P 15/ 18^{( . )}
A61P 25/ 20^{( . )}
A61P 35/ 00^{( . )}
C07D 209/ 14^{( . )}
C07D 401/ 14^{( . )}
C07D 471/ 10^{( . )}

(86)	International application number:
	PCT/US1996/020004

(87)	International publication number:
	WO 1997/021435 (19.06.1997 Gazette 1997/26)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

14.12.1995 US 19950008632P
16.02.1996 GB 19960003370

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	GOULET, Mark Rahway, NJ 07065 (US) BUGIANESI, Robert, L. Rahway, NJ 07065 (US) ASHTON, Wallace, T. Rahway, NJ 07065 (US) CHU, Lin Rahway, NJ 07065 (US) FISHER, Michael, H. Rahway, NJ 07065 (US) LIN, Peter Rahway, NJ 07065 (US) SMITH, Roy, G. Rahway, NJ 07065 (US) PONPIPOM, Mitree, M. Rahway, NJ 07065 (US) WYVRATT, Matthew, J. Rahway, NJ 07065 (US) YANG, Yi, Tien Rahway, NJ 07065 (US)

(74)	Representative: Thompson, John Dr., et al
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE