(19)
(11) EP 0 868 180 A1

(12)

(43) Date of publication:
07.10.1998 Bulletin 1998/41

(21) Application number: 96945082.0

(22) Date of filing: 20.12.1996
(51) International Patent Classification (IPC): 
A61K 31/ 00( . )
A61K 31/ 4164( . )
A61K 31/ 54( . )
A61P 9/ 10( . )
A61P 13/ 00( . )
A61P 13/ 12( . )
A61P 43/ 00( . )
C07D 417/ 14( . )
A61K 31/ 415( . )
A61K 31/ 4178( . )
A61P 9/ 00( . )
A61P 9/ 12( . )
A61P 13/ 08( . )
A61P 25/ 06( . )
C07D 405/ 06( . )
(86) International application number:
PCT/US1996/020739
(87) International publication number:
WO 1997/022341 (26.06.1997 Gazette 1997/27)
(84) Designated Contracting States:
BE CH DE ES FR GB IT LI NL

(30) Priority: 21.12.1995 US 19950009009P

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406-0939 (US)

(72) Inventors:
  • LUENGO, Juan Ignacio
    Audubon, PA 19403 (US)
  • XIANG, Jia-Ning
    Wayne, PA 19087 (US)

(74) Representative: Waters, David Martin, Dr., et al 
Smithkline Beecham plc Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) ENDOTHELIN RECEPTOR ANTAGONISTS