(19)
(11) EP 0 868 532 A1

(12)

(43) Date of publication:
07.10.1998 Bulletin 1998/41

(21) Application number: 96942803.0

(22) Date of filing: 22.11.1996
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 45/ 00( . )
C07K 2/ 00( . )
C07K 14/ 82( . )
C12Q 1/ 26( . )
A61K 38/ 00( . )
A61K 31/ 00( . )
A61P 35/ 00( . )
C07K 14/ 47( . )
C12N 5/ 10( . )
C12Q 1/ 34( . )
(86) International application number:
PCT/US1996/018848
(87) International publication number:
WO 1997/019194 (29.05.1997 Gazette 1997/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 24.11.1995 US 19950007543P

(71) Applicant: The Trustees of Columbia University in the City of New York
New York, NY 10027-6699 (US)

(72) Inventors:
  • FISHER, Paul, B.
    Scarsdale, NY 10583 (US)
  • SU, Zao-Zhong
    New York, NY 10032 (US)

(74) Representative: Lawrence, John, et al 
Barker Brettell 138 Hagley Road Edgbaston
Birmingham B16 9PW
Birmingham B16 9PW (GB)

   


(54) METHODS FOR DETERMINING COMPOUNDS CAPABLE OF INHIBITING THE ACTIVITIES OF THE Ha-ras ONCOGENE