(19)
(11) EP 0 871 481 A1

(12)

(43) Date of publication:
21.10.1998 Bulletin 1998/43

(21) Application number: 96940252.0

(22) Date of filing: 23.10.1996
(51) International Patent Classification (IPC): 
A61K 39/ 104( . )
A61K 47/ 48( . )
A61P 15/ 00( . )
A61P 35/ 00( . )
C07K 14/ 21( . )
C07K 16/ 26( . )
A61K 31/ 00( . )
A61K 51/ 00( . )
A61P 15/ 18( . )
C07K 7/ 23( . )
C07K 14/ 575( . )
A61K 39/ 00( . )
(86) International application number:
PCT/US1996/017008
(87) International publication number:
WO 1997/015325 (01.05.1997 Gazette 1997/19)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 27.10.1995 US 19950008018P
13.02.1996 GB 19960002878

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • HICKEY, Gerard, J.
    Rahway, NJ 07065 (US)
  • MOHN, Kenneth, L.
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James, et al 
European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) PSEUDOMONAS EXOTOXIN AS IMMUNOGENIC CARRIER IN SYNTHETIC CONJUGATE VACCINES