(19)

(11)

EP 0 871 745 A1

(12)

(43) Date of publication: 21.10.1998 Bulletin 1998/43 (21) Application number: 96907403.0 (22) Date of filing: 11.03.1996

(51) International Patent Classification (IPC):  A01H 5/ 00( . ) A61P 1/ 00( . ) C12N 9/ 24( . ) C12N 15/ 09( . ) C12N 15/ 82( . ) C12R 1/ 685( . ) A61K 38/ 46( . ) C12N 1/ 15( . ) C12N 15/ 00( . ) C12N 15/ 56( . ) A61K 38/ 00( . ) (86) International application number: PCT/EP1996/001009 (87) International publication number: WO 1996/029416 (26.09.1996 Gazette 1996/43)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV SI (30) Priority: 17.03.1995 GB 19950005479 (71) Applicant: DANISCO A/S 1001 Copenhagen K. (DK)	(72) Inventors: MADRID, Susan, Mampusta DK-2950 Vedbaek (DK) RASMUSSEN, Preben DK-2800 Lyngby (DK) BARUCH, Anita DK-2600 Glostrup (DK) (74) Representative: Harding, Charles Thomas  D. Young & Co. 21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)