(19)
(11) EP 0 871 756 A2

(12)

(43) Date of publication:
21.10.1998 Bulletin 1998/43

(21) Application number: 96913061.0

(22) Date of filing: 19.04.1996
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 35/ 76( . )
A61P 9/ 00( . )
A61P 31/ 04( . )
A61P 35/ 00( . )
C07K 14/ 57( . )
C12N 5/ 00( . )
C12N 15/ 867( . )
A61K 35/ 14( . )
A61K 48/ 00( . )
A61P 29/ 00( . )
A61P 31/ 12( . )
A61P 37/ 00( . )
C07K 14/ 755( . )
C12N 5/ 10( . )
C12R 1/ 91( . )
(86) International application number:
PCT/US1996/005638
(87) International publication number:
WO 1996/033282 (24.10.1996 Gazette 1996/47)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 20.04.1995 US 19950425180

(71) Applicant: CHIRON CORPORATION
Emeryville, California 94608 (US)

(72) Inventor:
  • JOLLY, Douglas, J.
    Leucadia, CA 92024 (US)

(74) Representative: Irvine, Jonquil Claire 
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) HIGH EFFICIENCY EX VIVO TRANSDUCTION OF CELLS BY HIGH TITER RECOMBINANT RETROVIRAL PREPARATIONS