(19)

(11)

EP 0 871 777 A1

(12)

(43) Date of publication: 21.10.1998 Bulletin 1998/43 (21) Application number: 96942813.0 (22) Date of filing: 26.11.1996

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) G01N 33/ 543( . ) C40B 70/ 00( . ) C12Q 1/ 68( . ) G01N 33/ 566( . ) G01N 15/ 14( . ) (86) International application number: PCT/US1996/018939 (87) International publication number: WO 1997/020074 (05.06.1997 Gazette 1997/24)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI NL PT SE (30) Priority: 30.11.1995 US 19950564851 30.11.1995 US 19950565007 (71) Applicant: Mandecki, Wlodeck Libertyville, IL 60048 (US)	(72) Inventor: Mandecki, Wlodeck Libertyville, IL 60048 (US) (74) Representative: Baldock, Sharon Claire  BOULT WADE TENNANT, 27 Furnival Street London EC4A 1PQ London EC4A 1PQ (GB)